Human Evolution: Y-chromosome clues to human ancestry

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Human Evolution: Y-chromosome clues to human ancestry

The case for a recent expansion of modern humans from Africa has been strengthened by the finding of monomorphism in part of a Y-linked gene, consistent with the low variability seen in human mitochondrial DNAs.

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I-49: Human Y Chromosome ProteomeProject

The success of the Human Genome Project (HGP) has provided a blueprint for the approximately 20,000 gene-encoded proteins potentially active in all of the hundreds of cell types that make up the human body. Yet we still have limited knowledge about a majority of the gene-encoded proteins which are the “building blocks of life” and “cellular machinery”. It is estimated that for nearly half of th...

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Inferring human history: clues from Y-chromosome haplotypes.

molecules are organic elements of information storage imbued with imperfect copying processes. Thus, they are fundamental repositories of an organism's evolutionary history. The field of human molecular evolution is predicated on the concept that patterns of DNA sequence variation in living populations encode aspects of human heritage shaped by a constellation of evolutionary influences. The fr...

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I-3: Human Y Chromosome Proteome Project 2012 Update

The Human Genome Project has generated a blueprint for the approximately 20,300 gene-encoded proteins potentially active in any of 230 cell types that make up the human body (human proteome). However, based on the UniProtKB/Swiss-Prot database content, about 6000 of at the protein level; for many others, there is very little information related to protein function, abundance, subcellular locali...

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The human Y chromosome.

Despite its central role in sex determination, genetic analysis of the Y chromosome has been slow. This poor progress has been due to the paucity of available genetic markers. Whereas the X chromosome is known to include at least 100 functional genetic loci, only three or four loci have been ascribed to the Y chromosome and even the existence of several of these loci is controversial. Other fac...

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ژورنال

عنوان ژورنال: Current Biology

سال: 1995

ISSN: 0960-9822

DOI: 10.1016/s0960-9822(95)00224-7